Easiest way to plan, visualize, and document DNA cloning and PCR

SnapGene

SnapGene

  -  124 MB  -  Trial
  • Latest Version

    SnapGene 8.0.1 LATEST

  • Review by

    Juan Garcia

  • Operating System

    Windows 7 / Windows 7 64 / Windows 8 / Windows 8 64 / Windows 10 / Windows 10 64

  • User Rating

    Click to vote
  • Author / Product

    GSL Biotech LLC / External Link

  • Filename

    snapgene_8.0.1_win.exe

SnapGene is the easiest way to plan, visualize, and document your everyday molecular biology procedures. Customize the display of enzyme sites, features, primers, ORFs, DNA colors, and more. The map can be in a circular or linear format.

Take advantage of SnapGene’s efficient data handling to scan large DNA sequences with thousands of annotated features. Make insertions, deletions, replacements, and case changes. When a sequence is copied and pasted, features are automatically transferred. Annotate common features automatically, or annotate novel features manually.

Find common features in your DNA sequence using SnapGene’s extensive database. Additional features of your choosing can be added to a custom database.

It provides elegant, information-rich windows for simulating a variety of common cloning and PCR methods. Highlight unique restriction sites in bold font, or choose the automatically defined Unique Cutters or Unique 6+ Cutters enzyme set.

Use your own primers, or ask the app to design primers automatically. The product file stores the template and primers in its history. Assemble up to eight fragments. Select the fragments to be joined and their orientations, and Snap Gene will design primers.

Use a Sequence view to see at a glance whether two translated features are in the frame. If so, the translations are linked on the same line. If not, the translations are on separate lines. Use the powerful alignment tool to check whether an actual construct matches the simulated construct.

It automatically records operations to create a graphical history, and stores the ancestor constructs in the final file. Use the familiar, secure operating system of your computer to store and organize your Snap Gene files.

Export a sequence to GenBank or FASTA format. Export a map or simulated agarose gel to common image formats. Convert a sequence, map, or gel image to standard formats for use with other software.

The open exchange of information is crucial, so SnapGene and SnapGene Viewer provide options for reading and exporting common file formats.

Note: 30 days trial version. You need to request a free trial license in order to evaluate the SnapGene app.

  • SnapGene 8.0.1 Screenshots

    The images below have been resized. Click on them to view the screenshots in full size.

    SnapGene 8.0.1 Screenshot 1
  • SnapGene 8.0.1 Screenshot 2
  • SnapGene 8.0.1 Screenshot 3
  • SnapGene 8.0.1 Screenshot 4
  • SnapGene 8.0.1 Screenshot 5

What's new in this version:

Detailed Changes:
- Added MW Markers from Applied Biological Materials
- Various textual enhancements
- Added keyboard shortcut for Zoom

Fixed:
- Fixed various issues when moving unsaved files
- Fixed issues with storing and resurrecting ancestral sequences
- Fixed circularizing a single sequence
- Improved stability when editing annotations in Features and Primers views
- Show features/primers column header in lower pane when splitting the view
- Ensure when splitting the view both copies of Features or Primers views sort annotations and are filtered the same way
- Fixed issues with inverting selected annotations in Features and Primers views
- Fixed issues with inserting bases at the beginning of an aligned sequence
- Fixed various issues where qualifiers could be cut off in features view if they were long and need to wrap to fit in the window, have multiple lines of text, or a larger font size was used
- Improved display of CviJI⭑ on Windows
- Fixed an issue where "No Matches" was shown in Features or Primers view when no Features or Primers exist
- Improved placement of "No Matches" message
- Fixed an issue where the Golden Gate Cloning dialog would appear to never finish when in fact a cloning strategy was not possible because amplification of the insert to add Golden Gate sites results in activating one or more Golden Gate sites that previously were near the sequence ends but not flanked with enough bases to result in a cleavage site
- Fixed an issue where circularizing, linearizing, changing the topology, Make Protein, Add Primers, Import Features, and various other actions were being performed on a prior file and folder selection instead of the visible document
- Corrected link to User Guide link about Primers
- Updated feature label placement options to not be checked if feature labels are toggled off which allows you to select a placement and show labels with one click.
- Ensure quick actions are not shown if no files are selected in the file and folder panel
- Fixed various issues with user based licenses
- Fixed an issue where selecting Primers in Primers view did not properly update the sequence selection or allow you to copy Primers
- Fixed the Ctrl+E shortcut for Choose Enzymes on Windows
- Restored Date Added and Visibility to Primers view's Sort By dialog
- Restored Visibility to Features view's Sort By dialog
- Fixed issues with copying and pasting Primers into Microsoft Word
- Fixed an issue where the filter controls would fail to find matches in Features and Primers views if an annotation was not expanded
- Restored ability to manually install a license